Blar i forfatter "Jansen, Kirsten Maria"

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    • Impact of GLP-1 receptor agonist versus omega-3 fatty acids supplement on obesity-induced alterations of mitochondrial respiration 

      Jansen, Kirsten Maria; Dahdah, Norma; Gama-Perez, Pau; Schots, Pauke C.; Larsen, Terje; Garcia-Roves, Pablo M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-23)
      Objective: To compare administration of the glucagon-like peptide-1 (GLP-1) analogue, exenatide, versus dietary supplementation with the omega-3 fatty acid-rich Calanus oil on obesity-induced alterations in mitochondrial respiration.<p> <p>Methods: Six-week-old female C57BL/6JOlaHSD mice were given high fat diet (HFD, 45% energy from fat) for 12 weeks to induce obesity. Thereafter, they were ...

    • Modulation of Cardiometabolic Health by Dietary Supplementation with Calanus oil 

      Jansen, Kirsten Maria (Doctoral thesis; Doktorgradsavhandling, 2021-09-17)
      Obesity leads to alterations in myocardial metabolism, expressed as an increased utilization of fat for energy purposes at the expense of carbohydrate. This shift in energy metabolism is associated with impairment of ventricular function which can lead to heart failure. This thesis raises the question of whether dietary supplementation with Calanus oil, a novel marine oil derived from the marine ...

    • Obesity-induced alterations in the gut microbiome in female mice fed a high-fat diet are antagonized by dietary supplementation with a novel, wax ester–rich, marine oil 

      Schots, Pauke C.; Jansen, Kirsten Maria; Mrazek, Jakub; Pedersen, Alice Marie; Olsen, Ragnar Ludvig; Larsen, Terje Steinar (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-09)
      Dietary supplementation with calanus oil, a novel wax ester–rich marine oil, has been shown to reduce adiposity in high-fat diet (HFD)–induced obese mice. Current evidence suggests that obesity and its comorbidities are intrinsically linked with unfavorable changes in the intestinal microbiome. Thus, in line with its antiobesity effect, we hypothesized that dietary supplementation with calanus oil ...